Miikka Vikkula Selected Research

Vascular Malformations

10/2020	New and Emerging Targeted Therapies for Vascular Malformations.
1/2020	RASA1 mosaic mutations in patients with capillary malformation-arteriovenous malformation.
1/2020	Theranostic Advances in Vascular Malformations.
1/2019	Rapamycin and treatment of venous malformations.
10/2018	Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study.
12/2011	Radio-opaque ethylcellulose-ethanol is a safe and efficient sclerosing agent for venous malformations.
7/2008	Association of localized intravascular coagulopathy with venous malformations.

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Miikka Vikkula Research Topics

Disease

12	Neoplasms (Cancer) 01/2021 - 07/2008
7	Vascular Malformations 10/2020 - 07/2008
3	Lymphedema (Milroy Disease) 01/2020 - 06/2003
3	Pain (Aches) 09/2015 - 07/2008
3	Pheochromocytoma 06/2015 - 02/2003
2	Hemangioma (Angioma) 06/2022 - 11/2008
2	Hydrops Fetalis (Fetal Edema) 12/2021 - 06/2003
2	Cleft Lip (Harelip) 01/2021 - 11/2005
2	Myofibroma 08/2019 - 01/2017
2	Myofibromatosis 08/2019 - 01/2017
2	Hypertrophy 05/2018 - 06/2005
2	Cleft Palate (Palate, Cleft) 12/2016 - 11/2005
2	Hemorrhage 09/2015 - 07/2008
2	Paraganglioma (Paragangliomas) 06/2015 - 01/2009
2	Enchondromatosis (Ollier Disease) 04/2011 - 09/2008
2	Van der Woude syndrome 04/2009 - 11/2005
1	Fibromuscular Dysplasia 01/2022
1	Chylothorax 01/2021
1	Bone Diseases (Bone Disease) 01/2021
1	Fibrosarcoma 01/2021
1	Necrosis 01/2021
1	Essential Osteolysis 01/2021
1	Sarcoma (Soft Tissue Sarcoma) 01/2021
1	Thrombophilia 12/2020
1	Convalescence 12/2020
1	COVID-19 12/2020
1	Hereditary Elliptocytosis 01/2020
1	Glioma (Gliomas) 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2020
1	Hyperplasia 01/2020
1	Tuberous Sclerosis (Bourneville's Disease) 01/2020
1	Gingival Overgrowth 01/2020
1	Squamous Cell Carcinoma of Head and Neck 01/2020
1	Edema (Dropsy) 01/2020
1	Melanoma (Melanoma, Malignant) 01/2019
1	Retinal Detachment (Retinal Detachments) 01/2019
1	Uveal melanoma 01/2019
1	Neurofibromatoses (Neurofibromatosis) 01/2019
1	Vein of Galen Malformations 01/2019
1	Ankyloglossia 12/2018
1	Cleft palate X-linked 12/2018
1	Mucositis 10/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 05/2018
1	Migraine Disorders (Migraine) 05/2018
1	Starvation 01/2018
1	Blue rubber bleb nevus syndrome 01/2017

Drug/Important Bio-Agent (IBA)

9	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 06/2003
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2003
4	Sirolimus (Rapamycin)FDA Link 01/2021 - 09/2015
2	TOR Serine-Threonine KinasesIBA 01/2021 - 10/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 11/2008
2	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2020 - 07/2008
2	fibrin fragment D (D-dimer)IBA 12/2020 - 07/2008
2	IntegrinsIBA 01/2020 - 11/2008
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2019
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 08/2019 - 01/2017
2	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 08/2019 - 01/2017
2	Transcription Factors (Transcription Factor)IBA 12/2018 - 06/2003
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 05/2018 - 07/2008
2	Succinate Dehydrogenase (Fumarate Reductase)IBA 06/2015 - 01/2009
2	Interferon Regulatory FactorsIBA 04/2009 - 11/2005
2	Coloring Agents (Dyes)IBA 06/2005 - 12/2003
1	Propranolol (Inderal)FDA LinkGeneric 06/2022
1	CollagenIBA 01/2022
1	Angiopoietin-2IBA 12/2021
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2021
1	trametinibIBA 01/2021
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2021
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2021
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2021
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2021
1	Proto-Oncogene Proteins c-metIBA 01/2021
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2021
1	Pharmaceutical PreparationsIBA 12/2020
1	betrixabanIBA 12/2020
1	Antiviral Agents (Antivirals)IBA 12/2020
1	Heparin (Liquaemin)FDA LinkGeneric 12/2020
1	RivaroxabanIBA 12/2020
1	AnticoagulantsIBA 12/2020
1	AlpelisibIBA 10/2020
1	trans-sodium crocetinate (crocetin)IBA 01/2020
1	MineralsIBA 01/2020
1	Circulating Tumor DNAIBA 01/2020
1	Cell-Free Nucleic AcidsIBA 01/2020
1	SpectrinIBA 01/2020
1	EphrinsIBA 01/2019
1	Biological ProductsIBA 01/2019
1	ChromatinIBA 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 01/2019
1	Endothelin-1 (Endothelin 1)IBA 05/2018
1	Complementary DNA (cDNA)IBA 01/2018
1	Tyrosine Kinase InhibitorsIBA 01/2017
1	LigandsIBA 01/2017
1	Imatinib Mesylate (Gleevec)FDA Link 01/2017

Therapy/Procedure

9	Therapeutics 01/2021 - 01/2017
1	Catheters 01/2021
1	Contraindications 12/2020
1	Precision Medicine 01/2020
1	Ligation 01/2019